Neuropilin 1 antibody

Catalog No. ABIN7881805

The Rabbit Monoclonal anti-Neuropilin 1 antibody is suitable to detect Neuropilin 1 in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for Neuropilin 1 antibody (ABIN7881805)

Target: Neuropilin 1 (NRP1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Neuropilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: BGO-14

Product Details anti-Neuropilin 1 Antibody

Purpose: Neuropilin 1 Antibody / NRP1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Neuropilin 1 / NRP1 was used as the immunogen for the Neuropilin 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Neuropilin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Neuropilin 1 antibody at -20oC.

Target Details for Neuropilin 1

Target: Neuropilin 1 (NRP1)

Alternative Name: Neuropilin 1

Background: The NRP1 encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. [RefSeq]

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals