NFIA antibody

Catalog No. ABIN7881834

This Mouse Monoclonal antibody specifically detects NFIA in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for NFIA antibody (ABIN7881834)

Target: NFIA (Nuclear Factor I/A (NFIA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NFIA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: PCRP-NFIA-2C6

Product Details anti-NFIA Antibody

Purpose: NFIA Antibody / Nuclear Factor 1 A (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant protein fragment was used as the immunogen for the NFIA antibody.

Isotype: IgG2c

Application Details

Application Notes: Optimal dilution of the NFIA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the NFIA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NFIA

Target: NFIA (Nuclear Factor I/A (NFIA))

Alternative Name: NFIA

Background: Nuclear factor (NF) proteins are a family of CCAAT-box-binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA-binding domain, and activates transcription through a putatively novel, proline-rich, carboxy-terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, -globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

UniProt: Q12857