Recombinant ODC1 antibody

Catalog No. ABIN7881885

This Rabbit Monoclonal antibody specifically detects ODC1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant ODC1 antibody (ABIN7881885)

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ODC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ODC1-3636R

Product Details anti-ODC1 Antibody

Purpose: Recombinant ODC1 Antibody / Ornithine Decarboxylase

Purification: Protein A affinity chromatography

Immunogen: Recombinant human ODC-1 protein was used as the immunogen for this recombinant ODC1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant ODC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant ODC1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Alternative Name: ODC1

Background: Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

UniProt: P11926