The Mouse Monoclonal anti-Phosphoglucomutase 5 antibody is suitable to detect Phosphoglucomutase 5 in samples from Human. It has been validated for WB and IHC (p).
PGM5
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
Optimal dilution of the Aciculin antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
4 °C,-20 °C
Storage Comment
Store the Aciculin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
Phosphoglucomutase 5 (PGM5)
Alternative Name
Aciculin
Background
Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome.