Phosphoglucomutase 5 antibody

Catalog No. ABIN7881932

The Mouse Monoclonal anti-Phosphoglucomutase 5 antibody (Clone 14F8-F8) (ABIN7881932) specifically detects Phosphoglucomutase 5 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Phosphoglucomutase 5 antibody (ABIN7881932)

Target: Phosphoglucomutase 5 (PGM5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Phosphoglucomutase 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 14F8-F8

Product Details anti-Phosphoglucomutase 5 Antibody

Purpose: Aciculin Antibody / PGM5 / Phosphoglucomutase 5

Purification: Protein G affinity chromatography

Immunogen: The cytoskeletal fraction of the human myometrium tissue extract was used as the immunogen for the Aciculin antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the Aciculin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Aciculin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Phosphoglucomutase 5

Target: Phosphoglucomutase 5 (PGM5)

Alternative Name: Aciculin

Background: Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome.

UniProt: Q15124

Pathways: Cellular Glucan Metabolic Process