KCNJ6 antibody

Catalog No. ABIN7882006

The Mouse Monoclonal anti-KCNJ6 antibody is suitable to detect KCNJ6 in samples from Human. It has been validated for IHC (p).

Quick Overview for KCNJ6 antibody (ABIN7882006)

Target: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCNJ6 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KCNJ6-7559

Product Details anti-KCNJ6 Antibody

Purpose: GIRK2 Antibody / G protein activated inward rectifier potassium channel 2

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human KCNJ6 protein was used as the immunogen for the GIRK2 antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the GIRK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the GIRK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for KCNJ6

Target: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Alternative Name: GIRK2

Background: This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]

UniProt: P48051