Recombinant OCT4 antibody

Catalog No. ABIN7882013

The Rabbit Monoclonal anti-OCT4 antibody (Clone OCT4-6875R) (ABIN7882013) specifically detects OCT4 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant OCT4 antibody (ABIN7882013)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This OCT4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: OCT4-6875R

Product Details anti-OCT4 Antibody

Purpose: Recombinant Oct4 Antibody / POU5F1

Purification: Protein A/G affinity

Immunogen: A portion of amino acids1-134 was used as the immunogen for the recombinant Oct4 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Alternative Name: Oct4

Background: OCT4 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. OCT4 is a key regulator of self-renewal in embryonic stem cells, its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testes. OCT4 Ab is useful in the identification of primary as well as metastatic germ cell tumors.

UniProt: Q01860

Pathways: Stem Cell Maintenance