Recombinant OCT4 antibody

Catalog No. ABIN7882017

This Rabbit Monoclonal antibody specifically detects OCT4 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant OCT4 antibody (ABIN7882017)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This OCT4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: OCT4-7347R

Product Details anti-OCT4 Antibody

Purpose: Octamer-binding protein 4 Antibody / OCT4

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of the human protein was used as the immunogen for the Octamer-binding protein 4 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Octamer-binding protein 4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the Octamer-binding protein 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Alternative Name: Octamer-binding protein 4

Background: OCT4 (Octamer-binding protein 4) is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. OCT4 is a key regulator of self-renewal in embryonic stem cells, its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testes. OCT4 Ab is useful in the identification of primary as well as metastatic germ cell tumors.

UniProt: Q01860

Pathways: Stem Cell Maintenance