Recombinant OCT4 antibody

Catalog No. ABIN7882019

The Rabbit Monoclonal anti-OCT4 antibody (Clone OCT4-6847R) (ABIN7882019) specifically detects OCT4 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant OCT4 antibody (ABIN7882019)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This OCT4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: OCT4-6847R

Product Details anti-OCT4 Antibody

Purpose: POU5F1 Antibody / OCT4

Purification: Protein A/G affinity

Immunogen: Recombinant fragment from the human protein was used as the immunogen for the POU5F1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the POU5F1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the POU5F1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Alternative Name: POU5F1

Background: OCT4/POU5F1 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. It is a key regulator of self-renewal in embryonic stem cells, its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4/POU5F1 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testis.

UniProt: Q01860

Pathways: Stem Cell Maintenance