Recombinant PROX1 antibody

Catalog No. ABIN7882055

The Rabbit Monoclonal anti-PROX1 antibody (Clone AOGA-16) (ABIN7882055) specifically detects PROX1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant PROX1 antibody (ABIN7882055)

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PROX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AOGA-16

Product Details anti-PROX1 Antibody

Purpose: Prospero homeobox protein 1 Antibody / PROX1

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to PROX1 protein was used as the immunogen for the Prospero homeobox protein 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Prospero homeobox protein 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The Prospero homeobox protein 1 antibody can be stored at -20oC.

Target Details for PROX1

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Alternative Name: Prospero homeobox protein 1

Background: PROX1 is a homeobox transcription factor that orchestrates cell fate programs by binding target DNA motifs and recruiting co-regulators to modulate chromatin accessibility. It is widely studied for its roles in developmental patterning and maintenance of specialized cell identities, particularly within endothelial and neural lineages.

In vascular biology, PROX1 is a master regulator of lymphatic endothelial specification and maintenance, aligning gene expression with signaling inputs that guide vessel identity, remodeling, and tissue fluid balance. Beyond endothelium, PROX1 contributes to organ development and context-dependent transcriptional networks that shape differentiation, metabolism, and tissue architecture.

The Prospero homeobox protein 1 antibody enables specific detection of endogenous PROX1 in applications such as immunohistochemistry, immunofluorescence, western blot, and immunoprecipitation. Researchers use the Prospero homeobox protein 1 antibody from NSJ Bioreagents to quantify protein abundance, assess nuclear localization, and evaluate pathway engagement across primary tissues and model systems. With high specificity and consistent performance, the Prospero homeobox protein 1 antibody supports rigorous studies of transcriptional regulation, vascular biology, and cell differentiation.

UniProt: Q92786

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation