PRC1 antibody

Catalog No. ABIN7882088

The Rabbit Monoclonal anti-PRC1 antibody (Clone EH-16) (ABIN7882088) specifically detects PRC1 in WB. The antibody is reactive with Human samples.

Quick Overview for PRC1 antibody (ABIN7882088)

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PRC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: EH-16

Product Details anti-PRC1 Antibody

Purpose: PRC1 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human PRC1 was used as the immunogen for the PRC1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PRC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the PRC1 antibody at -20oC.

Target Details for PRC1

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Alternative Name: PRC1

Background: Protein regulator of cytokinesis 1 (PRC1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression. [UniProt]

UniProt: O43663