PDHB antibody

Catalog No. ABIN7882117

The Rabbit Monoclonal anti-PDHB antibody is suitable to detect PDHB in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for PDHB antibody (ABIN7882117)

Target: PDHB (Pyruvate Dehydrogenase beta (PDHB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PDHB antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AEAD-16

Product Details anti-PDHB Antibody

Purpose: PDHB Antibody / Pyruvate Dehydrogenase E1 beta subunit

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Pyruvate Dehydrogenase E1 beta subunit / PDHB was used as the immunogen for the PDHB antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PDHB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the PDHB antibody at -20oC.

Target Details for PDHB

Target: PDHB (Pyruvate Dehydrogenase beta (PDHB))

Alternative Name: PDHB

Background: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. [RefSeq]

UniProt: P11177

Pathways: Warburg Effect