RAB7L1 antibody

Catalog No. ABIN7882126

The Mouse Monoclonal anti-RAB7L1 antibody is suitable to detect RAB7L1 in samples from Human. It has been validated for WB.

Quick Overview for RAB7L1 antibody (ABIN7882126)

Target: RAB7L1 (RAB7, Member RAS Oncogene Family-Like 1 (RAB7L1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAB7L1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1789CT823-71-1-1

Product Details anti-RAB7L1 Antibody

Purpose: RAB7L1 Antibody

Purification: Protein G purified

Immunogen: Recombinant human RAB7L1 was used as the immunogen for the RAB7L1 antibody.

Isotype: IgG1

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the RAB7L1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the RAB7L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for RAB7L1

Target: RAB7L1 (RAB7, Member RAS Oncogene Family-Like 1 (RAB7L1))

Alternative Name: RAB7L1

Background: Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. [UniProt]

UniProt: O14966