RAPGEF3 antibody

Catalog No. ABIN7882135

The Rabbit Monoclonal anti-RAPGEF3 antibody is suitable to detect RAPGEF3 in samples from Human. It has been validated for WB.

Quick Overview for RAPGEF3 antibody (ABIN7882135)

Target: RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RAPGEF3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AEOG-18

Product Details anti-RAPGEF3 Antibody

Purpose: Epac1 Antibody / RAPGEF3

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Epac1 / RAPGEF3 was used as the immunogen for the Epac1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Epac1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Epac1 antibody at -20oC.

Target Details for RAPGEF3

Target: RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

Alternative Name: Epac1

Background: The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade.

UniProt: O95398

Pathways: cAMP Metabolic Process