SARS-CoV-2 NSP4 antibody

Catalog No. ABIN7882201

The Rabbit Polyclonal anti-SARS-CoV-2 NSP4 antibody is suitable to detect SARS-CoV-2 NSP4 in samples from Human. It has been validated for ELISA.

Quick Overview for SARS-CoV-2 NSP4 antibody (ABIN7882201)

Target: SARS-CoV-2 NSP4 (SARS-CoV-2 Non-Structural Protein 4 (SARS-CoV-2 NSP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS-CoV-2 NSP4 antibody is un-conjugated

Application: ELISA

Product Details anti-SARS-CoV-2 NSP4 Antibody

Purpose: SARS-CoV-2 NSP4 Antibody

Purification: Affinity purified

Immunogen: Amino acids HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKAggggDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC
YDTNVLEGSVAYESLRPDTRggggKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALN
DFSNSGSDVLYQPPQTSITSAVLQ were used as the immunogen for the SARS-CoV-2 NSP4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SARS-CoV-2 NSP4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SARS-CoV-2 NSP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SARS-CoV-2 NSP4

Target: SARS-CoV-2 NSP4 (SARS-CoV-2 Non-Structural Protein 4 (SARS-CoV-2 NSP4))

Alternative Name: SARS-CoV-2 NSP4

Target Type: Viral Protein

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF1ab, the largest gene, contains overlapping open reading frames that encode polyproteins PP1ab and PP1a. The polyproteins are cleaved to yield 16 nonstructural proteins, NSP1-16. Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based on similarity to other coronaviruses, include the papain-like proteinase protein (NSP3), 3C-like proteinase (NSP5), RNA-dependent RNA polymerase (NSP12, RdRp), helicase (NSP13, HEL), endoRNAse (NSP15), 2'-O-Ribose-Methyltransferase (NSP16) and other nonstructural proteins. SARS-CoV-2 nonstructural proteins are responsible for viral transcription, replication, proteolytic processing, suppression of host immune responses and suppression of host gene expression. The RNA-dependent RNA polymerase is a target of antiviral therapies.

UniProt: P0DTC1