SARS-CoV-2 NSP9 antibody
Quick Overview for SARS-CoV-2 NSP9 antibody (ABIN7882204)
Target
See all SARS-CoV-2 NSP9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- SARS-CoV-2 NSP9 Antibody
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Sequence
- NNELSPVALR QMSCAAGTTQ TACTDDNALA YYNTTKGGRF VLALLSDLQD LKWARFPKSD GTGTIYTELE PPCRFVTDTP KGPKVKYLYF IKGLNNLNRG MVLGSLAATV RLQ
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Purification
- Affinity purified
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Immunogen
- Amino acids NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ were used as the immunogen for the SARS-CoV-2 NSP9 antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the SARS-CoV-2 NSP9 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the SARS-CoV-2 NSP9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SARS-CoV-2 NSP9 (SARS-CoV-2 Non-Structural Protein 9 (SARS-CoV-2 NSP9))
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Alternative Name
- SARS-CoV-2 NSP9
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Target Type
- Viral Protein
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Background
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF1ab, the largest gene, contains overlapping open reading frames that encode polyproteins PP1ab and PP1a. The polyproteins are cleaved to yield 16 nonstructural proteins, NSP1-16. Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based on similarity to other coronaviruses, include the papain-like proteinase protein (NSP3), 3C-like proteinase (NSP5), RNA-dependent RNA polymerase (NSP12, RdRp), helicase (NSP13, HEL), endoRNAse (NSP15), 2'-O-Ribose-Methyltransferase (NSP16) and other nonstructural proteins. SARS-CoV-2 nonstructural proteins are responsible for viral transcription, replication, proteolytic processing, suppression of host immune responses and suppression of host gene expression. The RNA-dependent RNA polymerase is a target of antiviral therapies.
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UniProt
- P0DTC1
Target
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