SIRT4 antibody

Catalog No. ABIN7882276

The Rabbit Polyclonal anti-SIRT4 antibody is suitable to detect SIRT4 in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for SIRT4 antibody (ABIN7882276)

Target: SIRT4 (Sirtuin 4 (SIRT4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SIRT4 Antibody

Purpose: SIRT4 Antibody

Sequence: HLKPDVVFFG DTVNPDKVDF VHKRVKEAD

Purification: Antigen affinity purified

Immunogen: Amino acids HLKPDVVFFGDTVNPDKVDFVHKRVKEAD from the human protein were used as the immunogen for the SIRT4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SIRT4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SIRT4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SIRT4

Target: SIRT4 (Sirtuin 4 (SIRT4))

Alternative Name: SIRT4

Background: Sirtuin 4, also known as SIRT4, is a protein which in humans is encoded by the SIRT4 gene. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

UniProt: Q9Y6E7

Pathways: Negative Regulation of Hormone Secretion