SLIT2 antibody

Catalog No. ABIN7882279

The Rabbit Monoclonal anti-SLIT2 antibody is suitable to detect SLIT2 in samples from Human. It has been validated for WB.

Quick Overview for SLIT2 antibody (ABIN7882279)

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SLIT2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ACGF-19

Product Details anti-SLIT2 Antibody

Purpose: SLIT2 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human SLIT2 was used as the immunogen for the SLIT2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SLIT2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the SLIT2 antibody at -20oC.

Target Details for SLIT2

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Alternative Name: SLIT2

Background: Slit homolog 2 protein is thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. [UniProt]

UniProt: O94813

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration