Optimal dilution of the Prostein antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
-20 °C
Storage Comment
Aliquot the Prostein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
SLC45A3
(Solute Carrier Family 45, Member 3 (SLC45A3))
Alternative Name
Prostein
Background
Human prostein is a 553 aa protein identified by cDNA library subtraction and subsequent high-throughput microarray screening of prostate cancer. Prostein has multiple transmembrane domains. Prostein has been shown to be uniquely expressed in normal and cancerous prostatic tissues. By immunohistochemistry, prostein is expressed in the vast majority of normal and malignant prostatic tissues, regardless of grade and metastatic status. No protein expression is detected in normal and malignant tissue samples representing the great majority of essential tissues and tumors. In particular, prostein is expressed in most of poorly differentiated prostatic carcinoma, including small cell prostate carcinoma. Prostein is more specific and sensitive for prostatic carcinomas than PSA and PSAP.