Recombinant Splicing Factor 1 antibody

Catalog No. ABIN7882351

The Rabbit Monoclonal anti-Splicing Factor 1 antibody is suitable to detect Splicing Factor 1 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant Splicing Factor 1 antibody (ABIN7882351)

Target: Splicing Factor 1 (SF1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Splicing Factor 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: NR5A1-4368R

Product Details anti-Splicing Factor 1 Antibody

Purpose: Recombinant SF-1 Antibody / Steroidogenic Factor 1 / NR5A1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human SF-1 protein was used as the immunogen for the recombinant SF-1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant SF-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant SF-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Splicing Factor 1

Target: Splicing Factor 1 (SF1)

Alternative Name: SF-1

Background: Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.

UniProt: Q13285

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location