Recombinant SOX2 antibody
Quick Overview for Recombinant SOX2 antibody (ABIN7882358)
Target
See all SOX2 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- SOX2 Antibody (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogen
- A recombinant fragment of human SOX2 protein was used as the immunogen for the SOX2 antibody.
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Isotype
- IgG
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anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
KO Validated SOX2 Reactivity: Human WB, IF, FACS, ICC, IHC (p), IP, IHC (fro), CUT&RUN Host: Rabbit Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 227-317) antibodySOX2 Reactivity: Human, Mouse, Rat, Goat WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibodySOX2 Reactivity: Human, Mouse WB, IHC, ELISA Host: Mouse Monoclonal SOX2-1791 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibodySOX2 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119), (N-Term) antibodySOX2 Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB14026 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibodySOX2 Reactivity: Human, Mouse, Rat, Goat, Cow, Pig, Sheep, Zebrafish (Danio rerio), Dog, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibodySOX2 Reactivity: Human IHC, ELISA, ICC Host: Mouse Monoclonal 10F10 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (Middle Region) antibodySOX2 Reactivity: Human, Mouse, Rat, Goat, Cow, Sheep, Zebrafish (Danio rerio), Dog, Horse, Rabbit, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119) antibodySOX2 Reactivity: Human WB, IHC, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (C-Term) antibodySOX2 Reactivity: Human, Mouse WB, IF, ICC, CUT&RUN, ChIP-seq, ChIP Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal dilution of the SOX2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- -20 °C
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Storage Comment
- Aliquot the SOX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Alternative Name
- SOX2
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Background
- SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.
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UniProt
- P48431
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Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Target
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