Recombinant SSX2IP antibody

Catalog No. ABIN7882415

The Rabbit Monoclonal anti-SSX2IP antibody (Clone 30S65) (ABIN7882415) specifically detects SSX2IP in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant SSX2IP antibody (ABIN7882415)

Target: SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SSX2IP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 30S65

Product Details anti-SSX2IP Antibody

Purpose: SSX2IP Antibody / Synovial sarcoma X breakpoint protein 2 interacting protein

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human SSX2IP was used as the immunogen for the SSX2IP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SSX2IP antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the SSX2IP antibody at -20oC.

Target Details for SSX2IP

Target: SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))

Alternative Name: SSX2IP

Background: SSX2IP antibody detects synovial sarcoma X breakpoint protein 2 interacting protein, a centrosomal protein involved in cell division and spindle organization. SSX2IP contributes to centrosome maturation and stability, facilitating accurate chromosome segregation. It has also been implicated in ciliogenesis, reflecting its role in microtubule-based processes beyond mitosis.

Research using SSX2IP antibody has linked the protein to cancer progression. Altered expression of SSX2IP has been observed in hematologic malignancies and solid tumors, where it may affect proliferation and genomic stability. SSX2IP also plays a role in cell adhesion and migration, adding to its importance in tumor biology. In developmental contexts, its regulation of ciliogenesis connects it to congenital disorders tied to defective ciliary signaling.

Antibodies against SSX2IP are applied in western blot, immunofluorescence, and immunohistochemistry. These reagents enable investigation of centrosome integrity, mitotic processes, and ciliary dynamics. Clone validation ensures reproducible results across research applications.

UniProt: Q9Y2D8