Thyroglobulin antibody
Quick Overview for Thyroglobulin antibody (ABIN7882476)
Target
See all Thyroglobulin (TG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- TG Antibody / Thyroglobulin
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Purification
- Affinity purified
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Immunogen
- A synthetic peptide specific to human Thyroglobulin / TG was used as the immunogen for the TG antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the TG antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store the TG antibody at -20oC.
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- Thyroglobulin (TG)
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Alternative Name
- TG
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Background
- Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. [RefSeq]
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UniProt
- P01266
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Pathways
- Thyroid Hormone Synthesis
Target
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