Recombinant TRIP10 antibody

Catalog No. ABIN7882478

The Rabbit Monoclonal anti-TRIP10 antibody (Clone 28T70) (ABIN7882478) specifically detects TRIP10 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant TRIP10 antibody (ABIN7882478)

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TRIP10 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 28T70

Product Details anti-TRIP10 Antibody

Purpose: TRIP10 Antibody / CIP4

Purification: Affinity chromatography

Immunogen: A synthetic peptide from human Cdc42-interacting protein 4 / Thyroid receptor-interacting protein 10 protein was used as the immunogen for the TRIP10 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TRIP10 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the TRIP10 antibody at -20oC.

Target Details for TRIP10

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Alternative Name: TRIP10

Background: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. [UniProt]

UniProt: Q15642