Thyroperoxidase antibody

Catalog No. ABIN7882479

This Rabbit Monoclonal antibody specifically detects Thyroperoxidase in WB. It exhibits reactivity toward Human.

Quick Overview for Thyroperoxidase antibody (ABIN7882479)

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Thyroperoxidase antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AFFI-20

Product Details anti-Thyroperoxidase Antibody

Purpose: Thyroid Peroxidase Antibody / TPO

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human TPO / Thyroid peroxidase was used as the immunogen for the Thyroid Peroxidase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Thyroid Peroxidase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Thyroid Peroxidase antibody at -20oC.

Target Details for Thyroperoxidase

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Alternative Name: Thyroid Peroxidase

Background: The TPO gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA.

UniProt: P07202

Pathways: Thyroid Hormone Synthesis