Topoisomerase I antibody

Catalog No. ABIN7882503

This Rabbit Monoclonal antibody specifically detects Topoisomerase I in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Topoisomerase I antibody (ABIN7882503)

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Topoisomerase I antibody is un-conjugated

Application: Western Blotting (WB)

Clone: FIG-20

Product Details anti-Topoisomerase I Antibody

Purpose: TOP1 Antibody / Topoisomerase I

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Topoisomerase I / TOP1 was used as the immunogen for the TOP1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TOP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the TOP1 antibody at -20oC.

Target Details for Topoisomerase I

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Alternative Name: TOP1

Background: The TOP1 gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [RefSeq]

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance