Bax Inhibitor 1 antibody

Catalog No. ABIN7882547

The Rabbit Polyclonal anti-Bax Inhibitor 1 antibody (ABIN7882547) specifically detects Bax Inhibitor 1 in WB, IHC (p) and IF. The antibody is reactive with Human samples.

Quick Overview for Bax Inhibitor 1 antibody (ABIN7882547)

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bax Inhibitor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-Bax Inhibitor 1 Antibody

Purpose: BI-1 Antibody / Bax inhibitor 1 / TMBIM6

Sequence: RKINFDALLK FSHITPSTQQ HLK

Purification: Antigen affinity purified

Immunogen: Amino acids RKINFDALLKFSHITPSTQQHLK were used as the immunogen for the BI-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BI-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the BI-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Bax Inhibitor 1

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Alternative Name: BI-1

Background: Bax inhibitor 1 (BI-1) is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process, negative regulation of intrinsic apoptotic signaling pathway, and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma.

UniProt: P55061

Pathways: Response to Water Deprivation, ER-Nucleus Signaling