Recombinant UCHL3 antibody

Catalog No. ABIN7882622

The Rabbit Monoclonal anti-UCHL3 antibody (Clone 26U65) (ABIN7882622) specifically detects UCHL3 in WB and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Recombinant UCHL3 antibody (ABIN7882622)

Target: UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UCHL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 26U65

Product Details anti-UCHL3 Antibody

Purpose: UCHL3 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human UCHL3 was used as the immunogen for the UCHL3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the UCHL3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the UCHL3 antibody at -20oC.

Target Details for UCHL3

Target: UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))

Alternative Name: UCHL3

Background: UCHL3 (Ubiquitin carboxyl-terminal hydrolase isozyme L3) is a deubiquitinating enzyme that belongs to the ubiquitin C-terminal hydrolase family. It functions by processing ubiquitin precursors and recycling ubiquitin from ubiquitinated proteins, thereby maintaining cellular ubiquitin homeostasis. Researchers often use a UCHL3 antibody to explore its role in protein turnover and cellular quality control.

UCHL3 is widely expressed across tissues and has been linked to key biological processes including DNA repair, cell cycle regulation, and stress responses. Dysregulation of UCHL3 has been associated with cancer, neurodegeneration, and impaired protein degradation pathways. Employing a UCHL3 antibody provides insights into its diverse cellular functions and disease associations.

NSJ Bioreagents offers a high-quality UCHL3 antibody validated for applications such as western blot, immunohistochemistry, and immunoprecipitation. Using a UCHL3 antibody ensures sensitive and reproducible detection in studies of ubiquitin biology, proteostasis, and disease mechanisms.

UniProt: P15374

Pathways: Feeding Behaviour, Positive Regulation of fat Cell Differentiation