UGT1A10 antibody

Catalog No. ABIN7882635

This Rabbit Polyclonal antibody specifically detects UGT1A10 in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for UGT1A10 antibody (ABIN7882635)

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT1A10 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-UGT1A10 Antibody

Purpose: UDP-glucuronosyltransferase 1A10 Antibody / UGT1A10

Sequence: HIVHLEDHLF CQYLFRNALE IASEILQ

Purification: Antigen affinity purified

Immunogen: Amino acids HIVHLEDHLFCQYLFRNALEIASEILQ were used as the immunogen for the UDP-glucuronosyltransferase 1A10 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the UDP-glucuronosyltransferase 1A10 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the UDP-glucuronosyltransferase 1A10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for UGT1A10

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Alternative Name: UDP-glucuronosyltransferase 1A10

Background: UDP-glucuronosyltransferase 1-10 is an enzyme that in humans is encoded by the UGT1A10 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.

UniProt: Q9HAW8

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha