Recombinant WT1 antibody

Catalog No. ABIN7882701

This Mouse Monoclonal antibody specifically detects WT1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant WT1 antibody (ABIN7882701)

Target: WT1 (Wilms Tumor 1 (WT1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This WT1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MMWT1-1

Product Details anti-WT1 Antibody

Purpose: Recombinant Wilms Tumor 1 Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant human protein was used as the immunogen for the recombinant Wilms Tumor 1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Titering of the recombinant Wilms Tumor 1 antibody may be required for optimal performance.

2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Wilms Tumor 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Alternative Name: Wilms Tumor 1

Background: Wilms Tumor is a transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. [UniProt]

UniProt: P19544

Pathways: Tube Formation