GALR3 antibody (2nd Extracellular Loop)

Catalog No. ABIN7885010

The Rabbit Polyclonal anti-GALR3 antibody (ABIN7885010) specifically detects GALR3 in WB, IHC, IF, FACS and LCI. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GALR3 antibody (2nd Extracellular Loop) (ABIN7885010)

Target: GALR3 (Galanin Receptor 3 (GALR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Grade: Carrier-free

Product Details anti-GALR3 Antibody

Binding Specificity: 2nd Extracellular Loop, AA 159-172

Purpose: A Rabbit Polyclonal Antibody to Galanin Receptor Type 3

Predicted Reactivity: Rat,human - identical

Purification: Affinity purified on immobilized antigen.

Immunogen: SYYGTVRYGALELC, corresponding to amino acid residues 159-172 of mouse Galanin receptor type 3

Isotype: IgG

Application Details

Application Notes:

WB: 1:200

FC: 2.5 μg per reaction

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Comment:

Negative Control: (ABIN7235481)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Preservative: Without preservative

Storage: -20 °C

Storage Comment: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Target Details for GALR3

Target: GALR3 (Galanin Receptor 3 (GALR3))

Alternative Name: Galanin receptor type 3

Background:

Synonyms: Galanin receptor type 3, GALNR3, GAL3R

Description: Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known receptors, the Galanin receptor type 1 (GALR1), Galanin receptor type 2 (GALR2) and Galanin receptor type 3 (GALR3). The Galanin receptors belong to the G-protein coupled receptor superfamily.1-4Based on mRNA, the GALR1 is predominantly distributed in the central nervous system, spinal cord and dorsal root ganglia while GALR2 is abundant in both central and peripheral nervous systems. GALR3 mRNA is distributed in peripheral tissues such as the heart, spleen, and testis. However, its expression in the brain is still controversial.4,5

Gene ID: 14429

UniProt: O88853

Pathways: cAMP Metabolic Process, Feeding Behaviour