Netrin 1 antibody (Secreted)

Catalog No. ABIN7885159

The Rabbit Polyclonal anti-Netrin 1 antibody is suitable to detect Netrin 1 in samples from Mouse, Human and Rat. It has been validated for WB and IHC.

Quick Overview for Netrin 1 antibody (Secreted) (ABIN7885159)

Target: Netrin 1 (NTN1)

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Netrin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-Netrin 1 Antibody

Binding Specificity: AA 181-195, Secreted

Purpose: A Rabbit Polyclonal Antibody to Netrin-1

Predicted Reactivity: Mouse,human - identical

Purification: Affinity purified on immobilized antigen.

Immunogen: CRKMYNRPHRAPITK, corresponding to amino acid residues 181 - 195 of rat Netrin-1

Isotype: IgG

Application Details

Application Notes:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:300

IP: The optimal concentration should be determined by the user

Comment:

Negative Control: (ABIN7236010)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Preservative: Without preservative

Storage: -20 °C

Storage Comment: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Target Details for Netrin 1

Target: Netrin 1 (NTN1)

Alternative Name: NTN1

Background:

Synonyms: NTN1, MRMV4

Description: Netrins are a family comprised of five members: three secreted proteins (netrins 1, 3 and 4), and two glycosylphosphatidylinositol (GPI)-anchored membrane proteins, netrins G1 and G21. Netrin-1 is a diffusible long-range axonal guidance cue expressed in floor plate cells of the central nervous system. It is secreted in order to direct exons to their target1-3. Axon guidance by netrin-1 is implicated in multiple developing brain regions and developing neuronal types. It also plays a role in axon branching, synaptogenesis, cell migration, cell survival, and axon regeneration4.

Gene ID: 114523

UniProt: Q924Z9

Pathways: Regulation of Cell Size