Synapsin III antibody (C-Term, Extracellular)

Catalog No. ABIN7885549

The Rabbit Polyclonal anti-Synapsin III antibody is suitable to detect Synapsin III in samples from Human, Rat and Mouse. It has been validated for WB, IHC and IF.

Quick Overview for Synapsin III antibody (C-Term, Extracellular) (ABIN7885549)

Target: Synapsin III (SYN3)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synapsin III antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-Synapsin III Antibody

Binding Specificity: AA 510-523, C-Term, Extracellular

Purpose: A Rabbit Polyclonal Antibody to Synapsin III

Predicted Reactivity: Mouse,human - identical

Purification: Affinity purified on immobilized antigen.

Immunogen: (C)RPPVQGRSTSQQGE, corresponding to amino acid residues 510-523 of rat Synapsin III

Isotype: IgG

Application Details

Application Notes:

WB: 1:200-1:400

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:200

IP: The optimal concentration should be determined by the user

Comment:

Negative Control: (ABIN7237315)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Preservative: Without preservative

Storage: -20 °C

Storage Comment: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Target Details for Synapsin III

Target: Synapsin III (SYN3)

Alternative Name: Synapsin-3

Background:

Synonyms: Synapsin-3

Description: Synapsin 3 (Syn3) belongs to the synapsin family of neuronal phosphoproteins, vesicle-associated proteins that includes two additional members: Synapsin I and Synapsin II. Alternative splicing of the genes results in at least ten variants with various levels of homology.Synapsins are involved in synaptogenesis, synaptic transmission and synaptic plasticity and are required for the formation and maintenance of the reserve and recycling pools of synaptic vesicles through association with the actin cytoskeleton. Several protein kinases, including PKA, calcium-calmodulin regulated protein kinases and the mitogen-activated protein kinase (MAPK) use synapsins as their substrates1-4.Syn3 plays an important role in several disorders, including bipolar disorder, schizophrenia and epilepsy1.

Gene ID: 29130

UniProt: O70441