MARCKS antibody (pSer162) (Biotin)

Catalog No. ABIN745150

This Rabbit Polyclonal antibody specifically detects MARCKS in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for MARCKS antibody (pSer162) (Biotin) (ABIN745150)

Target: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCKS antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MARCKS Antibody (Biotin)

Binding Specificity: pSer162

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MARCKS around the phosphorylation site of Ser162

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MARCKS

Target: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Alternative Name: MARCKS

Background:

Synonyms: 80 kDa protein, 80K L, 80K L protein, 80K-L protein, 80KL, 81 kDa protein, light chain, light chain, MACS, MARCKS, MARCS, MARCS_HUMAN, MGC52672, myristoylated alanine rich C kinase substrate, Myristoylated alanine rich protein kinase C substrate MARCKS, 80K L, Myristoylated alanine rich protein kinase C substrate, Myristoylated alanine-rich C-kinase substrate, Phosphomyristin, PKCSL, PRKCSL, protein kinase C substrate 80 kDa protein light chain, Protein kinase C substrate.

Background: MARCKS, (Myristoylated Alanine-Rich C Kinase Substrate), is a member of a family of calmodulin binding proteins and is a major substrate for phosphorylation by protein kinase C (PKC). The phosphorylation of Ser152/156 can be used as a measure of PKC activation. Phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin.

Gene ID: 4082