N6-Methyladenosine antibody

Catalog No. ABIN7938032

The Rabbit Polyclonal anti-N6-Methyladenosine antibody is suitable to detect N6-Methyladenosine. It has been validated for DB.

Quick Overview for N6-Methyladenosine antibody (ABIN7938032)

Target: N6-Methyladenosine

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Dot Blot (DB)

Product Details

Purpose: N6-Methyladenosine (m6A) antibody (pAb)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against 6-Methyladenosine conjugated to KLH.

Isotype: IgG

Application Details

Application Notes: DB: 1 - 2 μg/mL dilution For N6-Methyladenosine (m6A), we also offer AbFlex N6-Methyladenosine (m6A) Recombinant Antibody (rAb). For details, see Catalog No. 91261.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details

Target: N6-Methyladenosine

Target Type: Chemical

Background: N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well.