Recombinant ATG7 antibody

Catalog No. ABIN7938048

The Rabbit Monoclonal anti-ATG7 antibody (Clone 2M8) (ABIN7938048) specifically detects ATG7 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant ATG7 antibody (ABIN7938048)

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ATG7 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 2M8

Product Details anti-ATG7 Antibody

Purpose: ATG7 antibody (rAb), 100 μl (Clone 2M8)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the ATG7 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:2000-1:10000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Alternative Name: ATG7

Background:

Background_Plain: ATG7 is an E1-like enzyme that is specifically involved in autophagosome formation and is essential for autophagy. As an autophagic-related protein it is required for linking to Atg12, Atg5 and Atg8, which are essential for ATG7 conjugation and autophagosome formation. ATG7 has been reported as an important regulator of autophagy with starvation-induced or chemotherapeutic agent treatment. The high expression level of ATG7 is related to the survival of patients with breast cancer. The isoforms of ATG7 protein range from 68 kDa to 78 kDa.

Aliases: APG7-LIKE, APG7L, GSA7, autophagy related 7, SCAR31

Molecular Weight: 78 kDa

Pathways: Response to Water Deprivation, Autophagy