Recombinant CLOCK antibody

Catalog No. ABIN7938095

The Rabbit Monoclonal anti-CLOCK antibody is suitable to detect CLOCK in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Recombinant CLOCK antibody (ABIN7938095)

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CLOCK antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1I23

Product Details anti-CLOCK Antibody

Purpose: CLOCK antibody (rAb), 100 μl (Clone 1I23)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the CLOCK fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:8000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for CLOCK

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Alternative Name: CLOCK

Background:

Background_Plain: Circadian locomoter output cycles protein kaput (CLOCK), also named as BHLHE8 or KIAA0334, is an 846 amino acid protein, which contains one bHLH domain, one PAC domain, and two PAS domains. CLOCK localizes in the nucleus and cytoplasm. CLOCK) is expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine, colon, leukocytes, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. ARNTL/2-CLOCKheterodimers activate E-box element (5'-CACGTG-3') transcription of a few proteins of the circadian clock, such as PER1 and PER2.

Aliases: KAT13D, bHLHe8, clock circadian regulator

Molecular Weight: 95 kDa

Pathways: Regulation of Lipid Metabolism by PPARalpha, Photoperiodism