Recombinant DDX3X antibody

Catalog No. ABIN7938101

The Rabbit Monoclonal anti-DDX3X antibody is suitable to detect DDX3X in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Recombinant DDX3X antibody (ABIN7938101)

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DDX3X antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 5C12

Product Details anti-DDX3X Antibody

Purpose: DDX3 antibody (rAb), 100 μg (Clone 5C12)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the DDX3 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:50000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for DDX3X

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Alternative Name: DDX3

Background:

Background_Plain: DDX3X, also named DBX, DDX3 and HLP2, belongs to the DEAD box helicase family and DDX3X/DED1 subfamily. It is an ATP-dependent RNA helicase. DDX3X acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. It is also involved in HIV-1 replication. DDX3X

Aliases: DEAD-box helicase, DDX3X

Molecular Weight: 73 kDa

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly