Recombinant HNRNPC antibody

Catalog No. ABIN7938266

The Rabbit Monoclonal anti-HNRNPC antibody is suitable to detect HNRNPC in samples from Human, Rat and Mouse. It has been validated for WB.

Quick Overview for Recombinant HNRNPC antibody (ABIN7938266)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HNRNPC antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 4F16

Product Details anti-HNRNPC Antibody

Purpose: HNRNPC antibody (rAb), 100 μg (Clone 4F16)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the HNRNPC fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:50000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: HNRNPC

Background:

Background_Plain: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C) is a member of the subfamily nuclear ribonucleoproteins (hnRNPs) involved in pre-mRNA processing, mRNA metabolism, and transport. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene (C1 and C2).

Aliases: Heterogeneous Nuclear Ribonucleoprotein C, hnRNP C, HNRPC

Molecular Weight: 32 kDa