Recombinant PTRF antibody

Catalog No. ABIN7938423

The Rabbit Monoclonal anti-PTRF antibody (Clone 3E15) (ABIN7938423) specifically detects PTRF in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant PTRF antibody (ABIN7938423)

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PTRF antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 3E15

Product Details anti-PTRF Antibody

Purpose: PTRF antibody (rAb), 100 μl (Clone 3E15)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the PTRF fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:60000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for PTRF

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Alternative Name: PTRF

Background:

Background_Plain: PTRFThis gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis.

Aliases: CAVIN1, CAVIN, CGL4, cavin-1, FKSG13, PTRF, polymerase I and transcript release factor, caveolae associated protein 1

Molecular Weight: 43 kDa