14-3-3 gamma antibody (AA 21-162) (Fluoro647)

Catalog No. ABIN7964744

The Rabbit Polyclonal anti-14-3-3 gamma antibody is suitable to detect 14-3-3 gamma in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for 14-3-3 gamma antibody (AA 21-162) (Fluoro647) (ABIN7964744)

Target: 14-3-3 gamma (YWHAG1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 14-3-3 gamma antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-14-3-3 gamma Antibody (Fluoro647)

Binding Specificity: AA 21-162

Purpose: Anti-14-3-3 gamma/YWHAG Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human 14-3-3 gamma/YWHAG recombinant protein (Position: D21-K162).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for 14-3-3 gamma

Target: 14-3-3 gamma (YWHAG1)

Alternative Name: YWHAG

Background:

Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

Gene ID: 7532

UniProt: P61981

Pathways: Myometrial Relaxation and Contraction, M Phase