OAS2 antibody (AA 35-742) (HRP)

Catalog No. ABIN7964829

The HRP-conjugated Rabbit Polyclonal anti-OAS2 antibody (ABIN7964829) specifically detects OAS2 in WB, IHC and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for OAS2 antibody (AA 35-742) (HRP) (ABIN7964829)

Target: OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAS2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-OAS2 Antibody (HRP)

Binding Specificity: AA 35-742

Purpose: Anti-OAS2 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse OAS2 shares 62.4%,77.5% amino acid (aa) sequence identity with human,rat ATF5,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse OAS2 recombinant protein (Position: H35-K742). Mouse OAS2 shares 62.4% and 77.5% amino acid (aa) sequence identity with human and rat ATF5, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for OAS2

Target: OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))

Alternative Name: OAS2

Background:

Background: 2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene. Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Involved in defense response to virus, regulation of lactation, and type I interferon signaling pathway. Acts upstream of or within RNA catabolic process, interleukin-27-mediated signaling pathway, and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol, membrane, and nucleoplasm. Is expressed in embryo. Orthologous to human OAS2 (2'-5'-oligoadenylate synthetase 2).

Gene Full Name: 2'-5' oligoadenylate synthetase 2

Gene ID: 246728

UniProt: E9Q9A9

Pathways: Hepatitis C