OAS2 antibody (AA 35-742)

Catalog No. ABIN7964833

This Rabbit Polyclonal antibody specifically detects OAS2 in WB, ELISA and FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for OAS2 antibody (AA 35-742) (ABIN7964833)

Target: OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-OAS2 Antibody

Binding Specificity: AA 35-742

Purpose: Anti-OAS2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse OAS2 shares 62.4%,77.5% amino acid (aa) sequence identity with human,rat ATF5,respectively.

Characteristics: Anti-OAS2 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse OAS2 recombinant protein (Position: H35-K742). Mouse OAS2 shares 62.4% and 77.5% amino acid (aa) sequence identity with human and rat ATF5, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse ELISA, 0.1-0.5 μg/mL, Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for OAS2

Target: OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))

Alternative Name: OAS2

Background:

Background: 2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene. Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Involved in defense response to virus, regulation of lactation, and type I interferon signaling pathway. Acts upstream of or within RNA catabolic process, interleukin-27-mediated signaling pathway, and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol, membrane, and nucleoplasm. Is expressed in embryo. Orthologous to human OAS2 (2'-5'-oligoadenylate synthetase 2).

Gene Full Name: 2'-5' oligoadenylate synthetase 2

Molecular Weight: 69 kDa

Gene ID: 246728

UniProt: E9Q9A9

Pathways: Hepatitis C