NT5C antibody (AA 35-179)

Catalog No. ABIN7965208

This Rabbit Polyclonal antibody specifically detects NT5C in WB, IHC, FACS and ELISA. It exhibits reactivity toward Human.

Quick Overview for NT5C antibody (AA 35-179) (ABIN7965208)

Target: NT5C (5',3'-Nucleotidase, Cytosolic (NT5C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NT5C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Grade: Carrier-free

Product Details anti-NT5C Antibody

Binding Specificity: AA 35-179

Purpose: Anti-NT5C Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-NT5C Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NT5C recombinant protein (Position: H35-R179).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NT5C

Target: NT5C (5',3'-Nucleotidase, Cytosolic (NT5C))

Alternative Name: NT5C

Background:

Background: 5', 3'-nucleotidase, cytosolic, also known as 5'(3')-deoxyribonucleotidase, cytosolic type (cdN) or deoxy-5'-nucleotidase 1 (dNT-1), is an enzyme that in humans is encoded by the NT5C gene on chromosome 17. This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: 5', 3'-nucleotidase, cytosolic

Molecular Weight: 24 kDa

Gene ID: 30833

UniProt: Q8TCD5