ABI2 antibody (AA 151-400) (HRP)

Catalog No. ABIN7965358

This Rabbit Polyclonal antibody specifically detects ABI2 in WB, ELISA and IHC. It exhibits reactivity toward Human and Rat.

Quick Overview for ABI2 antibody (AA 151-400) (HRP) (ABIN7965358)

Target: ABI2 (Abl-Interactor 2 (ABI2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABI2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ABI2 Antibody (HRP)

Binding Specificity: AA 151-400

Purpose: Anti-ABI2 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ABI2 recombinant protein (Position: H151-D400).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Alternative Name: ABI2

Background:

Background: Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene. Enables several functions, including SH3 domain binding activity, identical protein binding activity, and ubiquitin protein ligase binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction, positive regulation of cellular component organization, and zonula adherens assembly. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in several cellular components, including filopodium tip, lamellipodium, and nucleoplasm. Part of SCAR complex. Is active in adherens junction. Colocalizes with actin filament.

Gene Full Name: abl interactor 2

Gene ID: 10152

UniProt: Q9NYB9