ABI2 antibody (N-Term) (APC)

Catalog No. ABIN7965370

This Rabbit Polyclonal antibody specifically detects ABI2 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ABI2 antibody (N-Term) (APC) (ABIN7965370)

Target: ABI2 (Abl-Interactor 2 (ABI2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABI2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-ABI2 Antibody (APC)

Binding Specificity: N-Term

Purpose: Anti-Abl interactor 2 ABI2 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Alternative Name: ABI2

Background:

Background: ABI2 (ABL Interactor 2), is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al. (2000) mapped the ABI2 gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein, a central serine-rich region, 3 PEST sequences, which are implicated in susceptibility to protein degradation, several proline-rich stretches, and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast (1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.

Gene Full Name: abl interactor 2

Sequence Similarities: Belongs to the ABI family.

Gene ID: 10152

UniProt: Q9NYB9