ABL2 antibody (AA 1065-1182) (Fluoro594)

Catalog No. ABIN7965378

The Fluoro594-conjugated Rabbit Polyclonal anti-ABL2 antibody (ABIN7965378) specifically detects ABL2 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ABL2 antibody (AA 1065-1182) (Fluoro594) (ABIN7965378)

Target: ABL2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABL2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-ABL2 Antibody (Fluoro594)

Binding Specificity: AA 1065-1182

Purpose: Anti-ABL2 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human ABL2 recombinant protein (Position: T1065-R1182). Human ABL2 shares 97.5% amino acid (aa) sequence identity with mouse ABL2.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ABL2 recombinant protein (Position: T1065-R1182). Human ABL2 shares 97.5% amino acid (aa) sequence identity with mouse ABL2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ABL2

Target: ABL2

Alternative Name: ABL2

Background:

Background: Tyrosine-protein kinase ABL2, also known as Abelson-related gene (Arg), is an enzyme that in humans is encoded by the ABL2 gene. This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Gene Full Name: ABL proto-oncogene 2, non-receptor tyrosine kinase

Gene ID: 27

UniProt: P42684