ACP2 antibody (AA 31-88) (Fluoro594)

Catalog No. ABIN7965543

The Fluoro594-conjugated Rabbit Polyclonal anti-ACP2 antibody (ABIN7965543) specifically detects ACP2 in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for ACP2 antibody (AA 31-88) (Fluoro594) (ABIN7965543)

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACP2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-ACP2 Antibody (Fluoro594)

Binding Specificity: AA 31-88

Purpose: Anti-ACP2 Antibody Fluoro594 Conjugated

Predicted Reactivity: Human ACP2 shares 98.3%,96.6% amino acid (aa) sequence identity with mouse,rat ACP2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ACP2 recombinant protein (Position: R31-H88). Human ACP2 shares 98.3% and 96.6% amino acid (aa) sequence identity with mouse and rat ACP2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ACP2

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Alternative Name: ACP2

Background:

Background: Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.

Gene Full Name: acid phosphatase 2, lysosomal

Gene ID: 53

UniProt: P11117