ACPL2 antibody (AA 45-459) (FITC)

Catalog No. ABIN7965566

The Rabbit Polyclonal anti-ACPL2 antibody is suitable to detect ACPL2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for ACPL2 antibody (AA 45-459) (FITC) (ABIN7965566)

Target: ACPL2 (Acid Phosphatase-Like 2 (ACPL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACPL2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-ACPL2 Antibody (FITC)

Binding Specificity: AA 45-459

Purpose: Anti-PXYLP1 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PXYLP1 recombinant protein (Position: K45-D459).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ACPL2

Target: ACPL2 (Acid Phosphatase-Like 2 (ACPL2))

Alternative Name: PXYLP1

Background:

Background: PXYLP1 dephosphorylates the xylose (xyl) residue in the glycosaminoglycan (GAG)-protein linkage region of proteoglycans, which is required for biosynthetic maturation of the linkage region. Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.

Gene Full Name: 2-phosphoxylose phosphatase 1

Gene ID: 92370

UniProt: Q8TE99