ACPL2 antibody (AA 45-459)

Catalog No. ABIN7965571

This Rabbit Polyclonal antibody specifically detects ACPL2 in WB, FACS and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ACPL2 antibody (AA 45-459) (ABIN7965571)

Target: ACPL2 (Acid Phosphatase-Like 2 (ACPL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACPL2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Grade: Carrier-free

Product Details anti-ACPL2 Antibody

Binding Specificity: AA 45-459

Purpose: Anti-PXYLP1 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-PXYLP1 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PXYLP1 recombinant protein (Position: K45-D459).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ACPL2

Target: ACPL2 (Acid Phosphatase-Like 2 (ACPL2))

Alternative Name: PXYLP1

Background:

Background: PXYLP1 dephosphorylates the xylose (xyl) residue in the glycosaminoglycan (GAG)-protein linkage region of proteoglycans, which is required for biosynthetic maturation of the linkage region. Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.

Gene Full Name: 2-phosphoxylose phosphatase 1

Molecular Weight: 70 kDa

Gene ID: 92370

UniProt: Q8TE99